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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1012
All Species:
19.7
Human Site:
Y519
Identified Species:
54.17
UniProt:
Q9Y2L5
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L5
NP_055754.2
1435
160941
Y519
L
L
K
S
Q
S
K
Y
S
E
A
A
A
L
L
Chimpanzee
Pan troglodytes
XP_001159900
1435
160893
Y519
L
L
K
S
Q
S
K
Y
S
E
A
A
A
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537289
1433
160646
Y519
I
L
K
S
Q
S
K
Y
S
E
A
A
A
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001099630
1433
160332
Y519
I
L
K
S
Q
S
K
Y
A
E
A
A
A
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515270
1078
120406
F202
P
M
V
R
K
F
A
F
H
M
I
L
A
G
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085189
1446
161543
Y518
I
L
K
S
Q
S
K
Y
S
E
A
A
A
L
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649135
1319
147666
L443
F
M
F
G
H
Y
N
L
A
F
Q
S
Y
H
Q
Honey Bee
Apis mellifera
XP_395570
1294
146835
S418
N
K
K
G
V
S
R
S
L
F
S
A
T
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785733
1203
133420
D327
N
D
P
A
M
F
P
D
Q
V
S
E
G
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96.3
N.A.
N.A.
91
N.A.
66.1
N.A.
76.5
N.A.
N.A.
29.1
33
N.A.
34.5
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
N.A.
95.9
N.A.
70.9
N.A.
86.5
N.A.
N.A.
47.6
51.9
N.A.
50.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
6.6
N.A.
93.3
N.A.
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
N.A.
100
N.A.
26.6
N.A.
100
N.A.
N.A.
20
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
12
0
23
0
56
67
67
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
56
0
12
0
0
0
% E
% Phe:
12
0
12
0
0
23
0
12
0
23
0
0
0
0
0
% F
% Gly:
0
0
0
23
0
0
0
0
0
0
0
0
12
12
0
% G
% His:
0
0
0
0
12
0
0
0
12
0
0
0
0
12
12
% H
% Ile:
34
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
12
67
0
12
0
56
0
0
0
0
0
0
0
0
% K
% Leu:
23
56
0
0
0
0
0
12
12
0
0
12
0
56
56
% L
% Met:
0
23
0
0
12
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
56
0
0
0
12
0
12
0
0
0
12
% Q
% Arg:
0
0
0
12
0
0
12
0
0
0
0
0
0
12
12
% R
% Ser:
0
0
0
56
0
67
0
12
45
0
23
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% T
% Val:
0
0
12
0
12
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
56
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _